Substrate: Nuclear receptor corepressor 1 (Transcription factor)
Seq-ID: O75376 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-62763   NELFE_HUMAN
MINT-2735454   ZMY11_HUMAN
MINT-2867106   ATX1_HUMAN
MINT-4303286   DHX30_HUMAN
MINT-4303443   NR2E3_HUMAN
MINT-4303604   RBBP7_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription corepressor activity,
histone deacetylase binding,
promoter binding		 spindle microtubule,
transcriptional repressor complex		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
transcription from RNA polymerase II promoter,
chromatin modification,
negative regulation of JNK cascade,
spindle assembly
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 88 GSDRPQERRTSYEPFHPGPSP - 18669648
HTP
0.00
 - -
0.93
 - medium
S 158 AFGGKHEAPSSPISGQPCGDD - 15302935
HTP
0.13
 - -
0.90
 - medium
S 172 GQPCGDDQNASPSKLSKEELI - 15302935
HTP
1.00
 - -
0.82
 - medium
S 224 AKPPEPEKPVSPPPVEQKHRS - 18669648
HTP
1.00
 - -
0.90
 - medium
S 999 SSTSPCGTSKSPNREWEVLQP - 17081983
HTP
1.00
 - -
0.69
 - medium
S 1111 TLPYIKQEEFSPRSQNSQPEG - 18669648
HTP
1.00
 - -
0.74
 - medium
S 1450 AGETVRSRHTSVVSSGPSVLR - 18220336
HTP
1.00
 - -
0.71
 - medium
S 1472 TLHEAPKAQLSPGIYDDTSAR - 18220336
HTP
1.00
 - -
0.73
 - medium
S 1472 TLHEAPKAQLSPGIYDDTSAR - 18669648
HTP
1.00
 - -
0.73
 - medium
S 1533 PTQRESIPAKSPVPGVDPVVS - 17081983
HTP
1.00
 - -
0.78
 - medium
T 1672 ILVPHPGGTSTPPMDRITYIP - 18669648
HTP
0.23
 - -
0.74
 - medium
S 1977 ETPSDAIEVISPASSPAPPQE - 15302935
HTP
1.00
 - -
0.84
 - medium
S 1977 ETPSDAIEVISPASSPAPPQE - 18669648
HTP
1.00
 - -
0.84
 - medium
S 1981 DAIEVISPASSPAPPQEKLQT - 18669648
HTP
1.00
 - -
0.81
 - medium
S 2120 VHHQRPGSRVSPENLVDKSRG - 15302935
HTP
1.00
 - -
0.89
 - medium
S 2120 VHHQRPGSRVSPENLVDKSRG - 16964243
HTP
1.00
 - -
0.89
 - medium
S 2120 VHHQRPGSRVSPENLVDKSRG - 18669648
HTP
1.00
 - -
0.89
 - medium
S 2151 HVSSEPYEPISPPQVPVVHEK - 17081983
HTP
1.00
 - -
0.80
 - medium
S 2184 EPAEQRNDARSPGSISYLPSF - 15302935
HTP
1.00
 - -
0.67
 - medium
S 2184 EPAEQRNDARSPGSISYLPSF - 16964243
HTP
1.00
 - -
0.67
 - medium
S 2184 EPAEQRNDARSPGSISYLPSF - 18669648
HTP
1.00
 - -
0.67
 - medium
S 2187 EQRNDARSPGSISYLPSFFTK - 18669648
HTP
1.00
 - -
0.56
 - medium
S 2395 YNPLTMRMLSSTPPTPIACAP - 18669648
HTP
0.21
 - -
0.65
 - medium
T 2396 NPLTMRMLSSTPPTPIACAPS - 18669648
HTP
1.00
 - -
0.67
 - medium
T 2399 TMRMLSSTPPTPIACAPSAVN - 18669648
HTP
1.00
 - -
0.71
 - medium
S 2436 PLLSAQYETLSDSDD       - 17081983
HTP
1.00
 - -
0.71
 - medium
S 2436 PLLSAQYETLSDSDD       - 18669648
HTP
1.00
 - -
0.71
 - medium
S 2438 LSAQYETLSDSDD         - 17081983
HTP
0.00
 - -
0.61
 - medium
S 2438 LSAQYETLSDSDD         - 18669648
HTP
0.00
 - -
0.61
 - medium

Substrate: Nuclear receptor corepressor 1 (Transcription factor)
Seq-ID: ENSMUSP00000018645 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
transcription corepressor activity,
sequence-specific DNA binding transcription factor activity,
histone deacetylase regulator activity,
retinoid X receptor binding,
thyroid hormone receptor binding		 nuclear part,
cytoplasm		 cholesterol homeostasis,
definitive erythrocyte differentiation,
regulation of multicellular organism growth,
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation,
positive regulation of histone deacetylation,
circadian regulation of gene expression,
negative regulation of phosphoinositide 3-kinase cascade,
thalamus development,
negative regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 225 AKPPEPEKPVSPPPVEQKHRS - 19144319
HTP
1.00
 - -
0.90
 - low
S 1482 TLHEAPKAQLSPGLYDDSSAR - 19144319
HTP
1.00
 - -
0.73
 - low

Substrate: Nuclear receptor corepressor 1 (Transcription factor)
Seq-ID: Q60974 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-2981725   HDAC3_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein domain specific binding,
transcription corepressor activity,
promoter binding,
sequence-specific DNA binding transcription factor activity,
histone deacetylase regulator activity,
retinoid X receptor binding,
thyroid hormone receptor binding		 nuclear part,
cytoplasm		 chromatin modification,
transcription,
cholesterol homeostasis,
definitive erythrocyte differentiation,
regulation of multicellular organism growth,
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation,
positive regulation of histone deacetylation,
circadian regulation of gene expression,
negative regulation of phosphoinositide 3-kinase cascade,
thalamus development,
negative regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 224 AKPPEPEKPVSPPPVEQKHRS - 19144319
HTP
1.00
 - -
0.89
 - medium
S 2198 DPAEQRSDSRSPGSISYLPSF - 17242355
HTP
1.00
 - -
0.67
 - medium
S 2449 PLLSAQYETLSDSDD       - 17242355
HTP
1.00
 - -
0.68
 - medium
S 2451 LSAQYETLSDSDD         - 17242355
HTP
0.00
 - -
0.59
 - medium

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